<date> <host> kernel: kvm: <pid>: cpu0 disabled perfctr wrmsr: 0xc1 data 0xabcd
In /var/log/libvirt/qemu/<vm-name>.log, I'll see
block I/O error in device 'drive-virtio-disk0': Stale file handle (116)
Are you sure your network is sound. If you turn on debug logging on the NFS do you see anything interesting at the time you get the Stale file handle errors?