You can place the statement in /etc/sysconfg/static-routes.

This file will be used when the network starts up.

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From: centos-bounces@centos.org [mailto:centos-bounces@centos.org] On Behalf Of ABBAS KHAN
Sent: Tuesday, August 19, 2008 9:38 AM
To: CentOS mailing list
Subject: [CentOS] Is there a way to save the routing table permanently?

I'm adding the default gateway to the route through "route add default gw 10.10.10.10" which is also shown in "route -n" but the problem is that as soon as I restart the network through /etc/init.d/network restart; the route sets to default one...!
SO, my question is there any way to save the modified route permanently by hardcoding the changes?

Thanks.