Logwatch is reporting this error, which I'm going to assume has been occurring for a few years but doesn't affect sending/receiving emails, so I haven't chased it down, now I'm looking to fix that.
1 (06498-19) ClamAV-clamd: All attempts (1) failed connecting to /var/spool/amavisd/clamd.sock, retrying (1)
Since logwatch is reporting this it makes me wonder if it isnt rotating cleanly by logrotate and/or if the socket isn't being cleaned up properly so when it goe to create it, it can't because it is already there, but because all of the details are the same it works.