anne@xxxx.org: host mailhost.zen.co.uk[212.23.3.98] said: 550-Verification failed for anne@xxx.lan 550-Unrouteable address 550 Envelope Sender: Domain must resolve in DNS! (in reply to RCPT TO command)
It looks like your outgoing mail from your local user(s) needs to be masqueraded or the whole server does.