What's about all the other 165 packages announced in Up2date? Can I update these packages without furthermore problems?
Perfectly safe to go ahead and do. the only potential issue would be a timeout to the mirror you're updating from because around release time, EVERYONE is hitting the mirrors. You should also really use yum instead of up2date.
Now I get the message in Up2date, that the kernel-utils 2.4-13.1.83 marked to left out. Is this okay or can I update these kernel-utils too.
You'll want the updated kernel-utils, yes. That's what has smartd, cpuspeed, dmidecode and a bunch of other good utils in it.