[CentOS] [off-topic] Build packages in virtual machine

Hi

Sorry for the silly question, but is it safe to build packages, like 
rpms, in virtual machines (virtualbox) and use this packages in real 
machines? Some of these machines are CentOS and others ares Opensuse.

I need to build (or would be very useful to have) Ganglia 3.1.x

Thanks

Marcelo