[CentOS] 4kB sector size HDDs

Hello again.

Do any of you have one of the 'new' HDDs with 4kB Sectors currently in use?
I would upgrade to the 4kB disks but I don't know if this might be
problematic as I intend to use ZFS w/ RAIDz or at least a classic RAID6.
How might this affect performance under 5.5 and how do I go about setting up
the alignment of the partitions I use?

Kind regards

Dawid Horace