[CentOS] updating centOS5.3

Tue Oct 12 11:01:37 UTC 2010
John Doe <jdmls at yahoo.com>

From: Ritika Garg <ritikagarg25 at gmail.com>
>I have centOS5.3 installed in the system. I have never updated it but now am 
>planning to update. While doing "yum update", is there any possibility that the 

>update might hamper the execution of any software/application installed on the 
>system? Is there anything particular to note before updating the system? 

I think:
yum clean all && yum update glibc\*
yum clean all && yum update yum\* rpm\* python\*
yum update"

And watch out for the .rpmsave or .rpmnew files...