[CentOS] kernel panic on 5.6

Mon Apr 18 19:26:56 UTC 2011
Jerry Geis <geisj at pagestation.com>

I am getting:

kernel panic unable to mount root fs on unknown block (0,0)

This is just a normal box that I have use many a time to test install.
Basic one disk SATA 160G. Been using it for at least a year.

Is this that glibc issue hitting me? or something else?